Surgery for Cytoreduction

What is cytoreductive surgery (CRS)?

Cytoreductive surgery (CRS) is a surgical method that aims to remove all the visible cancer in patients with intra abdominal cancers that have spread to the peritoneum, which is the lining of the abdominal cavity (peritoneal carcinomatosis). Call us now at 84518 65944 or visit our website to book an appointment for Cytoreductive Surgery in Mumbai. Let us help you in your battle against peritoneal carcinomatosis.

Anal Fissure Treatment in Dadar, Mumbai
  • When combined with hyperthermic intraperitoneal chemotherapy (HIPEC), cytoreduction therapy is beneficial in cases of cancer that has developed or spread to the abdominal cavity, such as appendiceal cancer, pseudomyxoma peritonei, colon cancer, gastric cancer, ovarian cancer, and peritoneal mesothelioma.
  • These therapies are administered in the following order: cytoreductive surgery, followed by HIPEC.
  • Cytoreductive surgery removes the visible components of the tumor, leaving only the microscopic cells remaining. If the tumor has spread into other organs, it may be necessary to surgically remove those organs in order to free the affected area of the tumor. Some of the organs that may be removed include the gallbladder, spleen, a portion of the small or large intestine, and the lining of the abdominal wall (peritoneum).
  • Following surgery, HIPEC – Hyperthermic Intra-Peritoneal Chemotherapy – is used to destroy any residual microscopic cancer cells.
  • HIPEC involves the administration of a heated chemotherapeutic solution to the abdomen in order to destroy any residual malignant cells. When the treatment is completed, the chemotherapy solution is emptied from the abdomen and the incision is closed using sterile equipment.
  • The heated solution is kept around 42-43°C. This increases the penetration and the efficacy of the chemotherapy.

How is CRS different from regular surgery for abdominal cancer?

CRS is not the same as regular abdominal cancer surgery. Patients with peritoneal carcinomatosis (disease that has spread in the peritoneal cavity) are seldom recommended surgery because they are thought to have unresectable disease, or cancer that cannot be removed surgically. However, CRS has been shown to be effective in some patients with peritoneal carcinomatosis

Benefits of Cytoreductive Surgery

Cytoreductive Surgery along with HIPEC can lead to better survival compared to intra-venous (Systemic) Chemotherapy alone in carefully selected cases.

Cytoreductive Surgery Risks

The most frequent consequences after cytoreductive surgery are bleeding and infection. Other hazards connected with surgery include:

  • Formation of blood clots that may spread to other regions of the body
  • An enterocutaneous fistula is a connection between the intestines and the skin of the abdomen.
  • Anastomotic leak – a leak that may occur when sections of the intestines are surgically reconnected
  • Reduced calorie intake


Cytoreductive surgery with HIPEC takes 6-10 hours to complete. Depending on the type of cancer, the patient had to stay in the hospital for 7-10 days or longer. The healthcare staff urges the patient to keep a balanced combination of rest and exercise. While the patient may feel fatigued for about 2-3 months, subsequent to this, patients can get back to a normal life.

What is the cytoreductive surgery success rate?

In correctly selected patients and types of cancer, Cytoreductive surgery offers excellent success rates in controlling cancer which was once thought to be incurable.

For more information & consultation on Cytoreductive surgery (CRS) in Mumbai, contact us on 84518 65944 or simply fill in your name and number & one of our team member will get in touch with you soon. Our team of experts along with Dr. Chintamani Godbole, MS, DNB (Surgical Gastroenterology), FRCS (Edinburgh, UK), and Gastrointestinal surgeon will help you out in understanding your problem and guide you through every stage of your treatment. For hospital directions click here.

Dr. Chintamani Godbole GI Surgeon Mumbai

Dr. Chintamani Godbole

Consultant GI & Colorectal Surgeon


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