HIPEC (Hyperthermic intraperitoneal chemotherapy)
A novel method of administering chemotherapy is hyperthermic intraperitoneal chemoperfusion. Hyperthermic means heated. HIPEC injects hot chemotherapy drugs directly into the abdomen. HIPEC may provide new hope for individuals undergoing abdominal cancer therapy in which some advanced cancer cells have disseminated to the lining of the abdomen. Its purpose is to prevent these cells from mutating into new tumors and causing cancer to reoccur.
During HIPEC, doctors first remove any visible malignancies in the patient’s abdomen. A special machine pumps heated chemo liquid into the abdomen. Chemotherapy affects cancer cells and tumors that are too small to notice. The chemo is removed after 90 minutes.
HIPEC delivers chemotherapy straight to cancer cells in the belly. Heating the fluid may help increase chemotherapy medication absorption and eliminate small cancer cells that may remain in the abdomen after surgery. The procedure is conducted under general anesthesia and takes 6-9 hours, depending on its complexity. Contact us for advance HIPEC surgery in Mumbai.
Who is the ideal candidate for HIPEC?
- Not have had serious chronic conditions. Be in good enough health to have surgery.
- Have a less peritoneal cancer index score (which assesses tumor development and tumor reach)
- There must be no more than one bowel obstruction or partial obstruction.
- Have a category for epithelial cells (other cell types are considered cautiously)
What is the procedure for HIPEC surgery?
Before HIPEC is administered, the surgeon–using regular surgical methods–will remove any visible tumors that can be removed throughout the peritoneal cavity. This is referred to as cytoreductive surgery. Following cytoreductive surgery, in the operative environment, the surgeon will deliver HIPEC therapy.
Once all the visible tumors are removed inside the abdomen, the heated, sterilized chemotherapy fluid (with a temperature between 41-43 degrees celsius) is administered to the abdomen for roughly 1 ½ hour to penetrate and destroy the remaining cancer cells. Following that, the solution is drained from the abdomen and the incision is closed. The HIPEC treatment is intended to eliminate any remaining cancer cells while minimizing the negative effects of chemotherapy. HIPEC consists of two steps: cytoreductive surgery and hot chemotherapy.
Step 1 cytoreductive surgery: The surgeon conducts cytoreductive surgery to remove as much tumor growth as feasible from the abdominal cavity. HIPEC without surgery is ineffective because the chemo medicines cannot penetrate deep into malignant tumors.
Step 2: Chemotherapy: hot chemotherapy is given soon after surgery to prolong life and avoid cancer recurrence. Heated chemotherapy has employed standard chemotherapy medications such as Mitomycin C, cisplatin, doxorubicin and pemetrexed. Instead of injecting these medications into your blood, surgeons give them straight to the chest or abdomen.
What differentiates HIPEC from traditional chemotherapy?
A few types of cancer, especially those found in the abdominal region, are difficult to cure. Intravenous chemotherapy, unlike intraperitoneal chemotherapy, does not kill these tumors. According to HIPEC experts, the heat enhances the chemotherapy’s ability to destroy these cancer cells. The machine has the following features:
- High doses of chemotherapy are possible.
- Chemotherapy is administered successfully within the abdominal cavity.
- Chemotherapy has had a minimal effect on the rest of the body.
- If done properly, it improves the patient’s prognosis.
- Improves medication absorption and cancer cell susceptibility in the abdominal cavity.
Benefits of HIPEC Surgery
Patients who get HIPEC surgery have a number of benefits.
- Improves chemotherapeutic absorption and susceptibility of malignant cells
- Chemotherapy at high dosages is conceivable, allowing for intense treatment.
- Chemotherapy may be administered locally to the abdominal cavity.
- Chemotherapy has much less systemic adverse effects.
- Improves the outlook
Recovery Time After HIPEC Surgery:
Recovery time after HIPEC surgery varies from person to person, however it normally takes 10-12 weeks. Your doctors will explain all you need to know about the recovery process, including how to care for your incision wounds and promote healing.
The most challenging aspect of recovery is fatigue. It will most likely take two to three months. But subsequent to this, the patients can have an absolutely normal life.
For more information & consultation on HIPEC Surgery in Mumbai, contact us on 84518 65944 or simply fill in your name and number & one of our team member will get in touch with you soon. Our team of experts along with Dr. Chintamani Godbole, MS, DNB (Surgical Gastroenterology), FRCS (Edinburgh, UK), and Gastrointestinal surgeon will help you out in understanding your problem and guide you through every stage of your treatment. For clinic directions click here.